Association between immunoglobulin GM and KM genotypes and placental malaria in HIV-1 negative and positive women in western Kenya.

When further stratified based on PM and HIV status for the HWE test, the trend remains similar: there was no deviation for KM genotype frequency distribution in the HIV-1 negative women regardless of PM status or in the HIV-1 positive women without PM except a borderline significance of deviation in HIV-1 positive women with PM showing negative F(is) ( P = 0.05, F(is) = −0.18).

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Analysis of the Effect of Individual GM6 and KM Genotypes on PM Infection with or without HIV-1 In univariable analysis, a borderline significant association between GM6(+) and GM6(+/−) genotypes and PM in HIV negative women was found, women without PM having higher frequencies of these genotypes ( P a = 0.05, Table 2 ), but a similar association was not seen in HIV-1 positive women.

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