Critical appraisal and potential role of 223 Ra in therapy of mCRPC The pivotal Phase III randomized double-blind placebo controlled ALSYMPCA trial of 223 Ra demonstrated a highly significant OS improvement in docetaxel-pretreated or docetaxel-unfit men with symptomatic bone-metastatic CRPC and a very tolerable side-effect profile.
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Radium-223 chloride: a potential new treatment for castration-resistant prostate cancer patients with metastatic bone disease.
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