Barely Significant
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Prediction of contact residue pairs based on co-substitution between sites in protein structures.

PLoS One · 2013 · PMC3546969 · PMID 23342110

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an overall trendno p-value reported
It is clearly shown that there is an overall trend for PPV to decrease monotonically as increasing number of predicted site pairs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.