Androgen receptors and serum testosterone levels identify different subsets of postmenopausal breast cancers.

In the ER-negative group, elevated testosterone levels were found associated (borderline significance) with AR-absent expression (OR 2.82, 95% CI, 0.98-8.06).

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Our main finding was that elevated testosterone levels were associated with AR-highly-positive expression in ER-positive tumors (a highly significant relationship) but, surprisingly, elevated testosterone levels were also associated with AR-absent expression in ER-negative tumors (borderline significance).

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