Additionally, a marginally significant association with T2DM was observed for the recessive (FEM OR = 1.11, 95% CI 1.00–1.24) and co-dominant (FEM OR = 1.05, 95% CI 1.00–1.10) models.
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Associations between UCP1 -3826A/G, UCP2 -866G/A, Ala55Val and Ins/Del, and UCP3 -55C/T polymorphisms and susceptibility to type 2 diabetes mellitus: case-control study and meta-analysis.
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Similarly, heterogeneity among studies of the UCP1 -3826A/G polymorphism was effectively reduced (I 2 = 32.7% for the allele contrast model) by exclusion of one study [33] and the recalculated pooled OR almost reached statistical significance (OR = 0.89, 95% CI 0.79–1.00).