Functional and Developmental Analysis of CD4(+)CD25(+) Regulatory T Cells under the Influence of Streptococcal M Protein in Rheumatic Heart Disease.

Results In the isolated cell cultures, the values of correlation coefficient showed a highly significant positive correlation (r=0.754, P<0.01) between the number of the cellular proliferation for both nTregs and CD4 + T cells with or without M protein stimulation, which was recorded by immunoflouresence technique on days 0, 3, 5 and 7 of incubation ( figure 1 ).

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