highly significantP = 5 × 10 −20
In fact, we found a highly significant correlation ( R = 0.2 and P = 5 × 10 −20 ) between RNA accessibility and ribosome density around the translation start sites ( Fig. 4A ), and the peak correlation locates approximately 10 bases upstream of the translation start site, the 5′ position of the occupancy site of the first ribosome in yeast ( Ingolia et al. 2009 ).