Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?

Front Immunol · 2013 · PMC3562761 · PMID 23382730

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a marginal trendno p-value reported

Application of IL-10 for treatment of active rheumatoid arthritis (RA) likewise produced inconclusive results with, at best, a marginal trend toward amelioration of disease (Brennan, 1999 ).

also in 626 other papers

an unexpected trendno p-value reported

Surprisingly, there was an unexpected trend toward increased production of IL-6, IL-8, and TNFα upon IL-10 treatment that, however, did not reach the level of statistical significance in the group of patients investigated (Cooper et al., 2000 ).

also in 275 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.