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Optimising drug prescribing and dispensing in subjects at risk for drug errors due to renal impairment: improving drug safety in primary healthcare by low eGFR alerts.

BMJ Open · 2013 · PMC3563134 · PMID 23355668

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an increasing trendno p-value reported
This is of importance, especially since there is an increasing trend of clinical laboratories reporting the MDRD along with serum creatine, which is also recommended by national and international organisations. 26 60 Some guidelines advise a higher cut-off point for dose adjustments (creatine clearance 50–60 ml/min), 11 61 but this was expected to result in an amount of alerts exceeding an acceptable workload.

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