Human microRNAs originated from two periods at accelerated rates in mammalian evolution.

Mol Biol Evol · 2013 · PMC3563971 · PMID 23171859

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a decreasing trendno p-value reported

Consistent with this theory, we revealed a significant increase in the expression levels of miRNAs that originated during the most accelerated-rate period, that is, the initial phase of the hominoid lineage, amid a decreasing trend of the expression for younger miRNAs.

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