Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.

There was also no strong evidence for variation in the vitamin D allele score–BMI association by average BMI of the study (≤25 kg/m 2 versus ≥25 kg/m 2 ), although for the synthesis score the meta-regression coefficient was of borderline significance ( p meta-regression = 0.053, Figure S8 ; p meta-regression = 0.78 for metabolism score).

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