Long-term inhibition of xanthine oxidase by febuxostat does not decrease blood pressure in deoxycorticosterone acetate (DOCA)-salt hypertensive rats.

PLoS One · 2013 · PMC3564945 · PMID 23393607

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an obvious trendno p-value reported

Despite an obvious trend for reduced MAP in the febuxostat group in the last week of the study, no statistically significant difference was observed in MAP ( Fig. 1C ), heart rate ( Fig. 1D ), systolic or diastolic pressures (last treatment day: control SBP = 204±10, febuxostat SBP = 186±10; control DBP = 151±5, febuxostat = 137±7; mmHg) between the control and febuxostat-treated groups.

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