Pharmacogenetic Aspects of Antipsychotic Drug-induced Weight Gain - A Critical Review.

After 10 weeks' treatment there was a highly significant association of genotype with weight gain in which those patients carrying the minor T allele (22% of the sample) were protected from substantial (>7%) gain in weight following initial treatment with risperidone or chlorpromazine with a relative risk of 3.45. 9) This has, despite some failed replica

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