Meta-regression models to address heterogeneity and inconsistency in network meta-analysis of survival outcomes.

BMC Med Res Methodol · 2012 · PMC3570315 · PMID 23043545

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an increasing trendno p-value reported

(These study specific estimates were obtained with a model similar to Model 1, but now assuming independent study specific differences in scale, rather than exchangeable effects as obtained the random effects model.) From Figure 7 it can be inferred that for the comparisons DTIC + IFN versus DTIC and DTIC + non-IFN versus DTIC the treatment effects in terms of scale show an increasing trend over the years.

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