Other up-regulated genes such as SERPINB7 (Megsin), TM4SF1 (a member of the tetraspanin family), VGF (nerve growth factor inducible), and DKK1 (an inhibitor of WNT signaling) were preferentially increased at the high dose; At the late time point (72 h), gene expression changes were smaller compared to the 48 h time point, indicating an overall trend to return to levels found in the control group at low dose, but still up-regulated at high dose, as observed for GDF15 and CDNK1A.
← all excerpts
Epithelial cells as active player in fibrosis: findings from an in vitro model.
1
—
—