Acquired hypermethylation of the P16INK4A promoter in abdominal paraganglioma: relation to adverse tumor phenotype and predisposing mutation.

Endocr Relat Cancer · 2013 · PMC3573842 · PMID 23154831

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highly significantno p-value reported

High Z -scores for individual TSG promoters were also significantly associated with different clinical and genetic features including SDHB mutation (all save NORE1A ), paraganglioma tumor type (all), metastasis (all), and death of disease (all except RARB , with RASSF1A being highly significant) ( Table 3 ).

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