Cryptorchidism and testicular germ cell tumors: comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristics.

Analyses stratified on laterality of undescended testes relative to TGCT revealed an apparent trend: sRR estimates increased steadily in progression from TGCT arising in testes contralateral to unilateral CO [sRR = 1.5(95% CI = 0.9–2.6)], on unspecified side relative to unilateral CO [sRR = 3.5(95% CI = 2.7–4.7)], ipsilateral to unilateral CO [sRR = 5.4(95% CI = 3.7–7.8)], and in either testis following bilateral CO [sRR = 9.8(95% CI = 6.2–15.7)] (Figure 2A ; Table S3Ci ).

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