Barely Significant
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Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers.

PLoS One · 2013 · PMC3577907 · PMID 23437155

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The sentences

highly significantp<0.001actually significant
The difference in plasma IFNα levels between HIV-1-infected subjects on ART and HIV-1-infected subjects not on ART was highly significant (p<0.001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.