Biomechanical factors and physical examination findings in osteoarthritis of the knee: associations with tissue abnormalities assessed by conventional radiography and high-resolution 3.0 Tesla magnetic resonance imaging.

On the contrary, multiple MRI features (that is, LTF cartilage integrity, osteophytes in MTF, LTF and PF compartments and effusion) were found to be significantly associated with crepitus, while the association with MTF cartilage integrity was of borderline significance ( P = 0.050).

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Three MRI features were significantly associated with lower quadriceps strength - namely, cartilage integrity (that is, reduced cartilage thickness) in the PF compartment (β = -0.17, P = 0.041) (see Figure 1 ), effusion (β = -0.16, P = 0.049) and synovitis (β = -0.21, P = 0.011) (see Figure 2 ) - while a borderline significant association was found for MTF cartilage integrity (β = -0.15, P = 0.073).

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