Cartilage oligomeric matrix protein specific antibodies are pathogenic.

Arthritis Res Ther · 2012 · PMC3580587 · PMID 22906101

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a definite trendno p-value reported

Antibody reactivity to both rat and mouse COMP showed a definite trend of increasing serum titres, from day 14 onwards with a peak response around day 50.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.