This correlation was highly significant with breast cancers expressing estrogen receptor (ER+) or exhibiting lymph node metastasis (LN+) ( Figure 5A–C ) and was lower but still significant in breast cancers with ER− and LN− status ( Figure S5A and B ).
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Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8).
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