Voltage-sensor movements describe slow inactivation of voltage-gated sodium channels I: wild-type skeletal muscle Na(V)1.4.

Although 2 μM TTX shows a nonsignificant trend toward impeding slower components of DIV immobilization ( Table 2 ), this may result from a conformational change in DI with SI that is reflected in DIV as a result of strong cooperativity between the two domains ( Chanda et al., 2004 ).

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