highly significantP < 0.001
Excretion of cortisol in HFA group showed no significant alteration from the control group (Phase I: 43.8 ± 4.43 vs 46.5 ± 6.60, 95% CI 43.16-49.84 P = 0.179; Phase II: 21.1 ± 2.87 vs 22.5 ± 2.52, 95% CI 21.22-23.78 P = 0.352; Phase III: 9.9 ± 1.20 vs 9.0 ± 0.97, 95% CI 8.51-9.49 P = 0.177, post-hoc Bonferroni test) but showed a highly significant alteration at the phases I (74.3 ± 8.62 vs 46.5 ± 6.60, P < 0.001), II (62 ± 7.68 vs 22.5 ± 2.52, P < 0.001), and III (40 ± 5.73 vs 9 ± 0.97, P < 0.001) when compared to LFA group.