Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective.

Crit Care · 2012 · PMC3584720 · PMID 22424150

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borderline significantno p-value reported

Two meta-analyses [ 155 , 158 ] separately estimated treatment effects for IVIg and IVIgAM and found a strong treatment effect for IgM-enriched IVIg (risk ratio (RR) = 0.66; 95% confidence interval (CI) 0.51 to 0.85.) and a borderline significant effect for IVIg (RR = 0.81; 95% CI 0.70 to 0.93) [ 158 ].

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