Maximum tolerated dose evaluation of the AMPA modulator Org 26576 in healthy volunteers and depressed patients: a summary and method analysis of bridging research in support of phase II dose selection.

Drugs R D · 2012 · PMC3585695 · PMID 22852579

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

an overall trendp = 0.09so close (0.05 < p ≤ 0.1)

An overall trend for the dose effect was found for dn-C max,ss (p = 0.09) and was significant for dn-AUC 12,ss (p = 0.03).

also in 4,871 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.