Met is the most frequently amplified gene in endometriosis-associated ovarian clear cell adenocarcinoma and correlates with worsened prognosis.

Met knockdown in ES-2 cells, an OCC cell line without Met amplification, showed a partially significant decrease in cell numbers by the cell viability assay using MTT assay compared with control shRNA ( Fig. 8B ), and this was mostly due to increased apoptosis in these cells ( Fig. 8C ).

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