Pitfalls in experimental designs for characterizing the transcriptional, methylational and copy number changes of oncogenes and tumor suppressor genes.

PLoS One · 2013 · PMC3589351 · PMID 23472150

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closest p · 2.0× alpha

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boldest claim

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marginally significantp<0.1so close (0.05 < p ≤ 0.1)

Thus, it would be more reasonable to evaluate the reliability of DE genes identified in only one dataset for a cancer type using the change directions of those genes showing at least marginally significant changes (e.g., p<0.1) in another dataset.

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