at the edge of significancep = 0.06
The binding of all of the ligands to BCA resulted in a trend to fewer exchanged BCA hydrogens relative to the case when BCA alone was incubated in D 2 O; this decrease was statistically significant ( p <0.05) for SA-OH, SA-Gly 1 , SA-Gly 3 , and SA-Gly 4 and at the edge of significance ( p = 0.06) for SA-Gly 2 and SA-Gly 5 .