Meta-analysis on four prospective studies including 7475 people showed a modest decrease in fracture risk of 4% per 50 pmol/L increase in vitamin B 12 levels, which was borderline significant (RR = 0.96, 95% CI = 0.92 to 1.00).
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Vitamin B12, folate, homocysteine, and bone health in adults and elderly people: a systematic review with meta-analyses.
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