Discrete-state stochastic models of calcium-regulated calcium influx and subspace dynamics are not well-approximated by ODEs that neglect concentration fluctuations.

Comput Math Methods Med · 2012 · PMC3594940 · PMID 23509597

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may be significantno p-value reported

However, during resting conditions, the deviation may be significant, and concentration fluctuations due to the small subspace volume could influence channel dynamics (Sections 2.2 – 2.4 ).

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