Atrophy rates in asymptomatic amyloidosis: implications for Alzheimer prevention trials.

PLoS One · 2013 · PMC3599038 · PMID 23554933

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.2100

boldest claim

The sentences

borderline significantp = 0.07so close (0.05 < p ≤ 0.1)

Across the group as a whole there was still a significant relationship between SUVR and hippocampal atrophy rate (p = 0.02); the relationship with ventricular expansion was now significant (p = 0.04), and with whole brain atrophy rate borderline significant (p = 0.07).

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failed to reach significancep = 0.21not close (p > 0.1)

There was a significant association between total hippocampal volume loss and baseline SUVR (independent of age) in the PiB-positive (p = 0.02, R 2 = 0.2) but not PiB-negative group (p = 0.7) ( Figure 1B,C ), although the difference in slopes failed to reach significance (p = 0.21).

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