Barely Significant
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Alternative processing of the U2 small nuclear RNA produces a 19-22nt fragment with relevance for the detection of non-small cell lung cancer in human serum.

PLoS One · 2013 · PMC3603938 · PMID 23527303

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highly significantno p-value reported
Nonetheless, the potential of miR-U2-1 to address an urgent medical need – that of accurately identifying patients with early lung cancer so that they can be targeted for potentially curative surgical resection – is highly significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.