Barely Significant
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Cytokine levels in the serum of healthy subjects.

Mediators Inflamm · 2013 · PMC3606775 · PMID 23533306

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a decreasing trendno p-value reported
A decreasing trend has been found for MIP-1 β , IL-18, GRO- α , MIF, SCF, SCGF- β , IL-2R α , SDF-1 α , and TRAIL, showing that these molecules are mainly produced during childhood and youth with respect to adulthood.

also in 47,180 other papers

an increasing trendno p-value reported
Cytokines with Significantly Higher Levels in Adults with respect to Children IL-17 and Eotaxin showed an increasing trend as age grows.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.