Estimating the burden of pneumococcal pneumonia among adults: a systematic review and meta-analysis of diagnostic techniques.

PLoS One · 2013 · PMC3615022 · PMID 23565216

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an increasing trendno p-value reported

The proportion of pneumococcal pneumonia that was bacteremic demonstrated an increasing trend in studies with more severe disease, which is consistent with findings that bacteremia is more common among patients with severe disease [26] .

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