Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young).

No Changes in Pancreatic Function or Morphology of TgCEL mice After Long-term Cerulein Exposure At the end of the long-term cerulein exposure there was a borderline significant difference in weight development between the four groups TgCEL/PBS, Control/PBS, TgCEL/Cerulein and Control/PBS, although post hoc analyses did not reveal significant differences between any of the groups ( Figure 5A ; ANOVA p-value 0.04, Bonferroni post-hoc p-values >.05; mean body weight of 33±5.4, 33±3.9, 27±4.8, 30±3.8 g for the four groups, respectively).

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