Another osmolyte, o-phosphocholine, demonstrated an increasing trend from diabetic 1 wk to 15 wks.
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Systemic perturbations of key metabolites in diabetic rats during the evolution of diabetes studied by urine metabonomics.
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The sentences
Therefore, detection of endogenous metabolic variations in the entire body as diabetes developing and progressing becomes highly significant.
This by-product exhibited a decreasing trend in the urine of diabetic rats from 1 wk to 15 wks, compared with the control.