Divergence of mammalian higher order chromatin structure is associated with developmental loci.

The clustering observed was found to be highly significant, and we identified 159 unexpectedly large (at least 400 Kb; p<1e-04) clusters of divergent regions with a median size of 800 Kb ( Figure 3 ; Table S2 ).

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regions that may have marginally failed to reach significance in the test for divergence above) within runs of divergent regions. 159 large divergent regions were discovered at the same, orthologous locations in the human and mouse genomes ( Table S3 ).

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