Additional lncRNAs functional in proliferation and with anti-apoptotic roles are still being discovered (Hu et al., 2011 ), while other lncRNAs which have not yet been functionally validated are emerging as highly significant cancer biomarkers (Gloss et al., 2012 ).
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Challenging paradigms: long non-coding RNAs in breast ductal carcinoma in situ (DCIS).
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