A highly significant correlation was found between the average methylation values for the MSC and the average methylation values for the chondrocytes in promoter regions (r 2 = 0.78), with the methylation states of the vast majority of promoters remaining unchanged [ 11 ].
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Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells.
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