Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli.

Nat Biotechnol · 2013 · PMC3622156 · PMID 23503680

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highly significantno p-value reported

To detect significant modules (even when no single trait is highly significant), we constructed modules initially based on permissive cutoffs for trait significance and then applied stringent criteria to filter significantly large modules, based on permutation tests.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.