Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX).

BMJ · 2013 · PMC3629902 · PMID 23599318

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highly significantno p-value reported

Despite some narrowing over time, the difference in the primary outcome measure remained highly significant at five years.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.