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Dynamic modular architecture of protein-protein interaction networks beyond the dichotomy of 'date' and 'party' hubs.

Sci Rep · 2013 · PMC3631766 · PMID 23603706

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an increasing trendno p-value reported
For example, module 9 was enriched with ‘cell cycle' and ‘pseudohyphal growth' (a pattern of cell growth occurs in conditions of nitrogen limitation) proteins, and it displayed higher co-expression in the sporulation process ( Figure 4 ), whereas module 7 was enriched with ‘protein biosynthesis and catabolism' proteins and also showed an increasing trend of co-expression at the condition of environmental changes or DNA damage 24 25 26 .

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