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The inhibitory effect of small interference RNA protein kinase C-alpha on the experimental proliferative vitreoretinopathy induced by dispase in mice.

Int J Nanomedicine · 2013 · PMC3632628 · PMID 23626468

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an increasing trendno p-value reported
Recently, there has been an increasing trend in inducing the PVR model in the eyes of mice and rabbits using dispase. 22 – 26 , 28 , 34 Dispase, a neutral protease isolated from Bacillus polymyxa , is able to harvest and culture cells due to its ability to cleave the basal membrane in various tissues, and can be used as an intravitreal injection material to induce PVR.

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