Barely Significant
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Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment.

Nat Immunol · 2013 · PMC3633104 · PMID 23563689

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp=1.2×10 −37actually significant
When we compared these normal HSC commitment-associated DMRs with the DMRs identified in Satb1-deficient HSCs, we found a highly significant overlap (p=1.2×10 −37 ; hypergeometrical testing), with 37% shared hypermethylated DMRs and 15% shared hypomethylated DMRs (overall 22% shared DMRs) ( Supplementary Fig. 6e ).

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