Structure and interactions of the human programmed cell death 1 receptor.

The second issue is that the ∼4-fold higher affinity of human PD-L2 versus PD-L1 is not observed in mice, arguing against affinity differences being highly significant (the affinity of the PD-1/PD-L1 interaction is in fact slightly higher in mice: K d ∼29.8 μ m versus ∼38.4 μ m ).

also in 132,142 other papers