Barely Significant
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Creatinine-or cystatin C-based equations to estimate glomerular filtration in the general population: impact on the epidemiology of chronic kidney disease.

BMC Nephrol · 2013 · PMC3637126 · PMID 23496839

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highly significantno p-value reported
Moving from strictly creatinine-based equations (MDRD or CKD-EPI) to cystatin C-based or combined equations will decrease prevalence of stage 3 CKD by half, which is highly significant from an epidemiological point of view.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.