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HIV-1 Env C2-V4 diversification in a slow-progressor infant reveals a flat but rugged fitness landscape.

PLoS One · 2013 · PMC3639246 · PMID 23638182

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a positive trendno p-value reported
Viral Entry As anticipated from previous publications [45] , [46] , there was a positive trend between Env-mediated infectivity ( Fig. 7A ) and average relative fitness values ( Fig. 7B ).

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