Variation in heterozygosity predicts variation in human substitution rates between populations, individuals and genomic regions.

I therefore reanalysed the data as a series of non-overlapping 2 Mb windows, revealing a highly significant positive correlation between diversity lost and substitution rate difference ( Figure 3 , correlation calculated on unbinned data with significance determined as a t-approximation, t [1286] = 6.3, P = 4.8×10 −10 ).

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