The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation.

BMC Anesthesiol · 2013 · PMC3643838 · PMID 23517311

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

ECMO circuits are not passive conduits for blood In critically ill patients not receiving ECMO, it has been shown PK changes can result in highly significant changes to drug exposure through interactions between the patient, pathology and the drug [ 9 - 12 ].

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.