Optimization of melanin production by Brevundimonas sp. SGJ using response surface methodology.

2 is a highly significant model ( p = <0.005).

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Also the values of pH ( X 1 ), tryptone ( X 3 ) and CuSO 4 ( X 8 ) were above the t -value limit that implies that these factors are possibly significant whereas the remaining factors were below the t -value limit which indicates their insignificance (Anderson and Whitcomb 2005 ).

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